| abstract |
A continuous Glomerular Filtration Rate (GFR) estimation system may include a Foley catheter, a continuous urine creatinine sensor, and a urine output monitor. The continuous GFR estimation system computes creatinine clearance as CrCl = (Ucr x Uvol )/(Pcr X I mim), where Ucr is urine creatinine in mg/dL, UVol is urine volume in mL, Pcr is plasma (serum) creatinine in mL, and Imin is time in minutes. A Foley catheter may be used to withdraw urine from the bladder. The urine may be delivered to a urine output monitoi that provides the Uvol value over a time Imin. Attached to the catheter is the flow-thiough continuous urine creatinine sensor for providing the Ucr value.The remaining parameter is Pcr.Because serum creatinine levels do not change rapidly over time, a blood sample may be withdrawn prior to the start of the continuous GFR to obtain the PCr value. |