| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f6ee64e420ffdad3e2fb360c93302a0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate |
2007-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8ff91c5a8bc99de5e4cfc18dc5b0e8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_503a4ea074ac146db4a313b6bd7f4b98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e09b105d5f282fe10d432b576f7b2f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f3a82e929d8e397dba0a5fc563ab650
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4902e59ffc79c95c043774537f0437e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69356715b82975fef07228118f217637
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f81ef732deaf808cdee54e26b1c2fe83 |
| publicationDate |
2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008101554-A1 |
| titleOfInvention |
Pellets comprising an active substance matrix and a polymer coating, and a method for producing said pellets |
| abstract |
The invention relates to pellets containing active substances and having a polymer coating and a mean particle size of between 300 and 1100 µm. Said pellets contain a pharmaceutically active substance which is integrated into a polymer matrix consisting of at least one polymer. The pellets according to the invention are characterised in that they have a maximum friability of 0.1 %, measured with 200g of pellets on a 200 m sieving machine with a sieve diameter of 20 cm and 1.5 mm of shaking amplitude at a shaking frequency of 50 1/sec for 10 min in the presence of six rubber cubes having a 1.8 cm long edge. Said pellets also have a polymer coating consisting of an anionic (meth)acrylate copolymer on the condition that, during the release test according to USP, the pellets release no more than 10 % of the active substance in the artificial gastric juice at a pH of 1.2 after 120 min. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11654124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-PN20100027-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104983692-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101897674-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9241910-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4003323-A4 |
| priorityDate |
2007-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |