http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008096082-A2

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filingDate 2007-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd8369679db714f920998bbbd7382ec8
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publicationDate 2008-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008096082-A2
titleOfInvention Method for measuring the concentration of activated factor vii (fviia) in a sample
abstract The invention relates to a method for measuring in vitro or ex vivo the concentration of FVII in a sample, that comprises the following steps: mixing said sample with human plasma free of FVII and of at least another factor selected from FVIII, FIX and FXI; b) adding compounds that initiate the thrombine generation reaction, including a calcium ion source, a phospholipidic agent and a tissular factor; c) carrying out a thrombine generation test (TGT) on the reaction medium thus obtained in order to a provide a thrombinogram with parameters; d) comparing at least one of the parameters of the thrombinogram with a homologous parameter of standard thrombinograms, each standard thrombinogram being obtained with a fixed reference concentration of FVIIa in said reaction medium in a range of 1 pM to 5 nM; and e) deducing from step d) a measure of the concentration of FVIIa in the sample included in said range.
priorityDate 2006-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 24.