| abstract |
Aspects of the invention relate to tetanus toxin C fragment conjugated to a MRI contrast agent, iron nanoparticle, or biodegradable nanoparticle. Aspects of the invention relate to methods of determining neurodegeneration in a subject by administering a tetanus toxin C fragment conjugated to a MRI contrast agent, iron nanoparticle, or biodegradable nanoparticle and measuring axonal transport. |