| abstract |
The present invention is directed to an ophthalmic composition comprising alginate having a minimum of about 0 % and a maximum of about 50 % guluronic units bound to an adjacent guluronic unit as a percentage of the total number of monomelic units in the alginate. The composition further includes a cationic antimicrobial agent. The alginate set forth above forms less deactivating complexes with cationic antimicrobial agent, and thus, the composition has improved preservative efficacy. |