| abstract |
Disclosed herein are medical devices, such as implantable devices (e g stents), comprising at least one coating covering at least a portion of the device in the form of film. The film may be a dry film and comprise at least one lipid bilayer and at least one pharmaceutically effective agent. Alternatively, the film may comprise at least one lipid, not necessarily in bilayer form, and at least one pharmaceutically effective agent. When the devices comprising the at least one lipid bilayer are exposed to an aqueous fluid, liposomes are released,encapsulating the pharmaceutically effective agent. The coatings may be placed directly on the device, or applied to a substrate attached to the device. |