Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7daa1d5a3e55441e9a87fabeb207eb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ef089df43cc4d7ce19dd32d44b6227 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
filingDate |
2007-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f62c7283b0a0f3717b43e1497e179ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_104e4ed60e132b2c9a6ec948565b92e6 |
publicationDate |
2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008076918-A2 |
titleOfInvention |
Anti-cancer agents and androgen inhibition activity compound |
abstract |
A qualitative 3D pharmacophore model (a common feature based model or Catalyst HipHop algorithm) developed from well-known natural product androgen receptor down-regulating agents (ARDAs). The 3D pharmacophore model is used as a template in virtual screening compounds for new ARDAs. ARDA compounds and compounds that strongly inhibit the growth of human prostate LNCaP cells. The compounds may be used in compositions and methods of inhibiting cell proliferation of a cancer and methods of preventing or treating cancer, including prostate cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3585768-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104151303-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2962649-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012017166-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107709290-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013063321-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016175290-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018290979-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591290-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9469606-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11648234-B2 |
priorityDate |
2006-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |