Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2bcdaf19dbae3e3484396642af2c3ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49a97f691c40b30d6cbb73a6eeb83167 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35f7946ecae59cd4a54ff59e51b551ec |
publicationDate |
2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008074488-A2 |
titleOfInvention |
Construction and use of transfection enhancer elements |
abstract |
Nucleic acids comprising a nucleic acid moiety and two or more transfection enhancer elements (TEE' s) according to the general formula (I): Hydrophobic moiety - pH-responsive hydrophilic moiety, wherein said pH sensitive hydrophilic moiety of said TEE is independently a weak acid having a pka of between 4 and 6.5 or is a zwitterionic structure comprising a combination of acidic groups with weak basis having a pKa of bwteeen 4.5 and 7. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3992288-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010004054-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010004054-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014056590-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018033492-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4011380-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2143726-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894962-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8957191-B2 |
priorityDate |
2006-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |