| abstract |
A transdermal drug delivery system (100) that provides a self-regulatmg closed loop system for the delivery of drugs or other therapeutic agents through a user's skin. The transdermal system includes a substrate (105), a sensing system (115) for detecting the saturation level of the therapeutic agent in an individual's blood stream, and a drug delivery system for increasing the amount of therapeutic agent delivered to the individual using the transdermal system. Using a transdermal system that has a self-contained sensing system and drug delivery system, the transdermal systems of the present invention do not require external monitors and/or power supplies, such that the resulting transdermal systems are closed-loop and self -regulating. |