| abstract |
The present invention relates to 2-Aminoquinoline derivatives which are represented by the general formula (I) wherein R1, R2 and X are as defined in the specification as 5-HT5A receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. Compounds of general formula I are useful in the prevention and/or treatment of anxiety depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, withdrawal from abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders or gastrointestinal disorders. |