| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_658df3b9d24eb5224b37aaf605741db6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_207b5c9674b1ea865e2f22361d59d14d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_918328706cfba550d69f731f99409fc5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32ffb7c841d0e087da3c37c8f68ee191 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 |
| filingDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55e26490a548b1b69f46121766144117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e71490d82d1a2d875d04a5ba34780bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0893094e0421c0d2df5cb2025aa623 |
| publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008067491-A2 |
| titleOfInvention |
Materials and methods for treating diseases caused by genetic disorders using aminoglycosides and derivatives thereof which exhibit low nephrotoxicity |
| abstract |
Various aspects related to the preparation of congeners of the aminoglycosides gentamicin such as the congener C2 and using this compound or derivatives thereof and pharmaceutically active salts to treat diseases that involve genetic mutations which introduce a missense or premature stop codon into a gene. Still other aspects include treating human or animal patients with the gentamicin congener C2 and derivatives and pharmaceutical salt thereof to overcome, or to at least mitigate, the symptoms of disease and disorders such as some forms of Becker's or Duchenne muscular dystrophy, Hurler's Syndrome and Cystic Fibrosis that have as their etiology the presence of a premature stop codon in a gene whose proper expression is necessary for good health. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016196964-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10555961-B2 |
| priorityDate |
2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |