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filingDate 2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c5c484011ac262d2445785dbd354ba1
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publicationDate 2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008067399-A3
titleOfInvention Controlled-release multi-layer formulation of piperazine-piperidine antagonists and agonists of the 5-th1a receptor having enhanced intestinal dissolution
abstract The present invention relates to controlled-release beads comprising diquinoline- substituted piperazine-piperidine compounds, such as 5-fluoro-8- {4-[4-[(6-methoxyquinolin- 8-yl)piperazin-l-yl]piperidin-l-yl}quinoline, or pharmaceutically acceptable salts thereof; to multiple particulate formulations comprising such beads; to methods of preparing such beads; and to methods of treating 5-HTiA-related disorders using such beads and/or multiple particulate formulations.
priorityDate 2006-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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