http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008067338-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23fd0e3e83e43fc055dd00cf7ab3445f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_110f0008d6a2a8c013638feb6183dbd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bddc50154a85db7e1ba9d5f1e34bde2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-001 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate | 2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cdb9a05c1cf3d446c39990cf8d947dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da1de901f1eb9afd5962bbc54dcba468 |
publicationDate | 2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2008067338-A2 |
titleOfInvention | Biosynthetic pathway and genes required for tropodithietic acid biosynthesis in silicibacter tm1040 |
abstract | The symbiotic association between the roseobacter Silicibacter sp. TM1040 and the dinoflagellate Pfiesteria piscicida involves bacterial chemotaxis to dinoflagellate-produced dimethylsulfoniopropionate (DMSP), DMSP demethylation, and ultimately a biofilm on the surface of the host. Biofilm formation is coincident with the production of an antibiotic and a yellow-brown pigment. The antibiotic is a sulfur-containing compound, tropodithietic acid (TDA). Using random transposon insertion mutagenesis, 12 genes were identified as critical for TDA biosynthesis by the bacteria, and mutation in any one of these results in loss of antibiotic activity (Tda ) and pigment production. A biosynthetic and regulatory pathway for TDA biosynthesis in roseobacters is described. |
priorityDate | 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1061.