Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d19af9ee43224928aa4cfd20fdf78c88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d59a48ac8f31cc3b1c07c180502285fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53594a984d6cff01337384eb208f9a62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-51 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 |
filingDate |
2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96108efa9974e219527dd15a38949904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2feda22fa4c4a82cc4764164b13464a1 |
publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008067126-A2 |
titleOfInvention |
Methods for using aldhbr cells to supplement stem cell transplantation |
abstract |
The present invention relates to methods repairing, regenerating, and reconstituting tissues by transplanting at least two stem cell populations, wherein the first and the second population of stem cells are introduced into a subject separated by a time interval of about 2 to about 24 hours. The first population comprises stem cells derived from umbilical cord. The second population comprises ALDHbr cells. These ALDHbr cells can be administered to a patient immediately after isolation or can be primed in culture using a combination of cytokines for about 2 to about 7 days prior to transplantation. The methods of the invention are useful in accelerating time to neutrophil and/or platelet engraftment and immune reconstitution following myeloablative therapy. |
priorityDate |
2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |