| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4206f0f25fe9727fef5722200601a379
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fc2142c3f04084c2907d74ba80f537e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f12c1e4b116615e3219f70302352326
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec3d7a9a543c4214ef75cdabb2d0e04b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-01001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2007-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da6e73e8dcc70bc4dce3142198acbece
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dcb798fdfbc54ab7813d21f4a50be75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aac2fb783663d2a96bd7057492b8b801 |
| publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008066964-A2 |
| titleOfInvention |
Compositions and methods for inducing or inhibiting activities of selected human cells |
| abstract |
Polynucleotides encoding a mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to active drug are provided. Compositions and methods for sensitizing cells to a prodrug agent, inhibiting cell growth, treating drug addiction, and facilitating the metabolism of an organophosphate with this enzyme are also provided. In addition, a screening assay for identification of drugs activated by this enzyme is described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2700650-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014512379-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9116152-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2700650-A4 |
| priorityDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |