| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2da6e073139a660a8cb045758f939b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8639d317ced2073cbb124faa4ea7de4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c198757da18cf77dfbdcef00abb70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34e97dfd37992cfcb0d5eaf36d255f6e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04198d7432f544ac7320f31c654faf27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_184f1422ec1506ae516e08692c6bd486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6430ddcf001a1fa832c2e57f83fa126a |
| publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008065398-A2 |
| titleOfInvention |
Evolved orthogonal ribosomes |
| abstract |
There is provided a method for evolving an orthogonal rRNA molecule, comprising the steps of: providing one or more libraries of mutant orthogonal rRNA molecules and introducing the libraries into cells such that the orthogonal rRNA is incorporated into ribosomes to provide orthogonal ribosomes; providing one or more orthogonal mRNA molecules which (i) are not translated by natural ribosomes, and (ii) comprise one or more orthogonal mRNA codons; assaying the translation of the of the orthogonal mRNA and selecting the orthogonal rRNA molecules which translate the orthogonal mRNA, wherein the assay in step (c) requires translation of one or more orthogonal mRNA codons in the orthogonal mRNA; and orthogonal ribosomes incorporating such rRNA molecules. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102782132-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023285596-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011077075-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013514799-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-202110137-D0
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9340790-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2584037-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2584037-A4 |
| priorityDate |
2006-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |