Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e29ac5d787a37a2803b2d2a1b2ba917d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8604708bf089fd20eb331640921a7174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b3bbc15137a9b9655806f5cdec5f795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_681ef453b49379f1fe5be03ba5d25494 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7daa5abc6a15c256aa178ec92c5ce47e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a4c7b8d701e6a345ca685b95f629988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed4ace5a2305a45c8d9dd46de7d464d9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70535 |
filingDate |
2007-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f9f48f094edfbd5748f27b83ed7b88d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c04feba00b320fccd3a5820220ebda93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a084bc86bafa957fbb178d0e5f847332 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91c58f76297110efcaa07a253a3745c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f6692823e1a38d202b522c271a1a1a7 |
publicationDate |
2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008062383-A2 |
titleOfInvention |
Transgenic animal with enhanced immune response and method for the preparation thereof |
abstract |
The present invention provides a method for producing a transgenic (Tg) non-human animal capable of developing an enhanced humoral immune response against an antigen as compared to a non-transgenic control animal of the same species, comprising introducing into said non-human animal a genetic construct providing for enhanced MHC class I-related neonatal Fc receptor (FcRn) activity. Also provided a Tg non-human animal comprising a genetic construct providing for enhanced FcRn activity, as well as the use of such animal in a non- therapeutical method. Therapeutic genetic constructs and methods are also provided. The present invention further provides methods for producing immunoglobulins. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015036004-A1 |
priorityDate |
2006-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |