| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6210ab0cd344ae0175f01a43945923a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5419f16c4223126216563ed43e69b87b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cd8a617691cef181b2d9fe6442bfe9b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-50 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate |
2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f9f033415ee55c3a6009e92269533f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38388f42635609556f2b219af3ea4dbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1faae91e182390dc2bf8e3c7f94ebee0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c998dfa84da666aca13fad5f4c2e220f |
| publicationDate |
2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008062310-A2 |
| titleOfInvention |
Elimination of the bacteria that cause pierce's disease |
| abstract |
XyIeIIa fastidiosa is the cause of the Pierce's Disease in grapevines and other cultures of economic importance that are susceptible to the bacteria. Anti-Xylella fastidiosa substances were developed comprising hen scFv antibodies attached to a lytic peptide Cecropin Pl (CPI), a derivative of a nematode, expressed in M13 phages or in soluble form. The recombinant substance specifically eliminates 100% of the XyIeIIa fastidiosa in culture while using a concentration of 3.6 x IO(5) phages/bacterial in 28 hours of incubation. A scFv expressed in M13 phage eliminates 100% of the bacteria in a culture between 28 and 48 hours. A soluble scFv by itself or attached to the lytic peptide CP1 eliminates almost 100% of the XyIeIIa fastidiosa bacteria in culture. This strategy has a potential application to solve diseases in plants caused by bacteria. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015534983-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10499650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10499651-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014063070-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10212941-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9357785-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788052-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102093998-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102093998-A |
| priorityDate |
2006-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |