| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1990bcccaa0a52396469461e2f39b2a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a4783407e23a20dbe43d383a5d0fcb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d1e52d446de95dcd1d3c2ecc23901b7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6421 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b2cacc2843fb66d6e9dad5b3a27dda8 |
| publicationDate |
2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008061674-A2 |
| titleOfInvention |
Use of an animal model and method for testing drugs and treatments for cancer in humans |
| abstract |
The present invention relates to the use of a non-human animal in an animal model for studying cancer and/or for assaying novel treatments and drugs for treating cancer in humans, which animal has an alteration in its genome as compared to the wildtype animal, which alteration leads to a modified expression of Aph-1b. The alteration comprises for example the presence of only one copy of the Aph-1b gene as compared to two copies in the wild type genome or the presence of the SNP651 T>G mutation in the said gene. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012010904-A1 |
| priorityDate |
2006-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |