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publicationDate 2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008060521-A1
titleOfInvention Cell culture apparatus and associated methods
abstract A cell culture apparatus consists of a vessel or array of vessels, each comprising a substantially flat bottom and substantially vertical sides, and composed of a substantially gas permeable material. The inner bottom surface of the vessel is commonly textured to provide the cells with adequate features for attachment and spreading. The vessel may include an integral annular flange which can be used to suspend the vessel from a suspensory element of a rack structure. To promote cell attachment and growth, the inner surfaces of the vessel bottom and sides may be coated with commonly available bio- active materials. Cells cultured in the system commonly grow in three dimensipns for extended periods of time, and often produce significantly higher quantities of cellular products than cells grown in conventional labware.
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