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filingDate 2007-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b4202a182c55ebaeac9dd9a1c704b4f
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publicationDate 2009-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008055072-A3
titleOfInvention Compositions and methods for treating ocular diseases and conditions
abstract The present invention relates to compositions and methods for prevention and treatment of diseases and conditions, particularly ocular diseases and conditions, characterized by aberrant fibrogenesis or scarring, inflammation, and/or aberrant neovascularization or angiogenesis. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against the bioactive lipid, sphingosine-1 -phosphate, and its variants, which moieties are capable of decreasing the effective concentration of bioactive lipid being targeted. In one embodiment, the immune-derived moiety is a humanized monoclonal antibody that is reactive against sphingosine-1 -phosphate.
priorityDate 2006-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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