Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e2afd49631bff341129dcfd5e072ed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef416fe4f66ebb1021cecfb0ba5ae45d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c2cbdc3486aa305e48aab92b3c630eb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4727 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B20-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10 |
filingDate |
2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4165742f29b3f034e8c3602566b01ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aa186695441cb91ae430edd5814140f |
publicationDate |
2008-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008054354-A2 |
titleOfInvention |
Assays for s1oo inhibitors |
abstract |
Provided are methods of determining whether a compound is an inhibitor of an S1OO protein. The methods utilize a biosensor that comprises the S1OO protein that has a covalently bound fluorescent dye at an amino acid residue of the S1OO protein that becomes less exposed to the aqueous solution upon activation of the S1OO protein, where the fluorescent dye has decreased fluorescence when exposed to the aqueous solution than when protected from exposure to the aqueous solution. Also provided are methods of treating a subject having metastatic cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103952142-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103952143-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107088191-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113234835-A |
priorityDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |