http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008052718-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca65522d14ddb5d8cc14d1fa45d00d02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b50382de55f1c85aa8b8889f0829564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48c1c389e4b9206dbccdd39818887033 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 |
filingDate | 2007-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9566b916d80ff3d829984e526b773e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca14e02830a7421c82c33342be409f9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_858ed97f775cc53580589af09f37819e |
publicationDate | 2008-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2008052718-A1 |
titleOfInvention | Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples |
abstract | The invention relates to methods and apparatuses for determining factor Xa inhibitors, especially heparins and fractionated or low molecular weight heparins, and direct FXa inhibitors, in blood samples, which are characterized in that in a first step the blood sample is brought into contact with a detection reagent which comprises at least one thrombin substrate which consists of a peptide residue which can be eliminated by thrombin and which is amidically linked via the carboxyl end to an electrogenic substance, and with a known amount of factor X reagent and an activator reagent which brings about conversion of factor X into factor Xa, subsequently in a second step the amount or activity of the electrogenic substance which is eliminated from the thrombin substrate through the factor Xa-mediated thrombin activation, and/or the time course thereof, is determined as measured signal using electrochemical methods, and finally in a third step, by means of this measured signal, the amount of the factor Xa inhibitor in the sample of the blood to be investigated, or a measured quantity correlating therewith, in particular a clotting time correlating therewith, is ascertained. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10337048-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104714036-A |
priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.