http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008052288-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_834a0bddf5a027998ecc744dd6cac904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_880a361feb3a65ed8a47823432568bc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a546cdc09416c2330f849dbff964e1e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e865bb1da5f5539e248a80e574977904 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 |
| filingDate | 2007-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4f0a2eabc8bdb400d9fe34d94bab28b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45540f7537b1ce3de1eedff734598e94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf590dae31186fb7a0e11f14825c4f4 |
| publicationDate | 2008-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008052288-A1 |
| titleOfInvention | Dithiole compounds as cox inhibitors |
| abstract | A compound of formula (I) wherein: R1 and R2 are the same or different and are independently selected from H and a shielding group; X and Y are each independently selected from N and CH; R3 is hydroxy, alkoxy, acyloxy or an ester group; R4 is a direct bond to R5, -CH2- or -CH=; the broken line ----- represents an optional double bond between R4 and R5; and R5 is a 5- or 6-membered substituted or unsubstituted unsaturated heterocyclic or heteroaromatic ring, or R5 is a substituted heterocyclic ring containing the substituent = O or = S, wherein the heteroatom is selected from S, O or P, and wherein R5 is optionally attached to R4 through a substituent on the heterocyclic or heteroaromatic ring; or a pharmaceutically acceptable prodrug, metabolite, ester, salt, derivative, tautomer or isomer thereof. The compounds have utility as COX-inhibitors and for use in the treatment of pain, inflammation or a neurodegenerative disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014029197-A1 |
| priorityDate | 2006-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 357.