Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34b0f6e2818b55363b575b28c56fe291 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_244717e5f331a70037198f4c6cc937fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a0e1c2c4b397988b7846e59f1fc2fd7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-045 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2007-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9751b33c9cc6d3ca4ce3865db3e14f28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd3596d650ef7456379275b8ec36f87f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37e18b025df1b94476d881b3e0e3baab |
publicationDate |
2009-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008046107-A9 |
titleOfInvention |
Novel inhibitors of the egfr kinase targeting the asymmetric activating dimer interface |
abstract |
The invention provides methods and compositions for the modulation of EGFR activity, in particular, inhibition of EGFR activation through an allosteric mechanism is discloses, as is a method for targeted drug discovery and design based on models of the three dimensional structure of the kinase domains of the protein dimers. |
priorityDate |
2006-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |