Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47c4cefdfd4058d5e9e5c235ccb149bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71bedddeec02bc740429fc8dc6eacc63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af6d9a6a5a0749d7f412d82276b971c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785b1a9ccba4d22d7a430ce4dae50c58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cf3edbcc4eff0637b26151ddf7aeb4a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 |
filingDate |
2007-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62a5a0c9c405cfd6112f25afa95aa957 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_674bb57bc0920545b1774f0c64deadf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d44bae8618665aa38e91dc6e6bcd47a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b7880da2ed2b05b58449682625ae5c |
publicationDate |
2008-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008044144-A3 |
titleOfInvention |
Chiral tetra-hydro beta-carbolic derivatives and applications thereof as antiparasitic compounds |
abstract |
The invention relates to the use of chiral tetra-hydro β-carboline derivatives of formula (I) for the preparation of pharmaceutical composition for the prevention and/or the treatment of parasitic diseases involving parasites having a phosphodiesterase activity: or a pharmaceutically acceptable salt thereof, in which: - R1 and R2, identical or different, represent a hydrogen atom or a fluorine atom; - k is an integer equal to 0 or 1; - R3 is selected from the group consisting of: a phenyl ring optionally substituted a 3'-N-pyridine ring optionally substituted - R4 is a group selected in the group consisting of the following groups: -NH-A-R5, -NHC(O)-R5 and the groups of formulas (ll-a) to (ll-c) below: The invention also relates to some new chiral tetra-hydro β-carboline derivatives. |
priorityDate |
2006-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |