| abstract |
Disclosed is a biomolecule detection reagent which comprises a semiconductor nanoparticle and a biomolecule-detecting molecule uniformly present on the surface of the nanoparticle, and which shows less valiance of fluorescence intensity and less reduction/variation in fluorescence intensity. Specifically, the reagent has one detecting molecule capable of specifically binding to a biomolecule per one semiconductor nanoparticle. In the reagent, each of the semiconductor nanoparticles constituting a semiconductor nanoparticle aggregate has, on its surface, a detecting molecule capable of specifically binding to a biomolecule, and the standard deviation of the number of the detecting molecules on the surface of each of the semiconductor nanoparticles is 5% or lower. |