| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79da8d457a2e1f70413a9e1cb2efaf29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bc31573a86be92b723bc424b20d68ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25ab3f48716df9f405ba042e1f25f300
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6636b59c3149a23a6ae7feaa3984d05f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3ec15981c4c9238c95705f6af3c56ee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B33-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-585 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00 |
| filingDate |
2007-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68272d9eca8453c0ff39697b8385a08a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfceb089528678dc77c80481c73e72b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20ebd3aafb8b950bdbe57bbe8c6248b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91074dfd918a017a880a564faed49296 |
| publicationDate |
2008-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008030624-A3 |
| titleOfInvention |
Nanoparticles for two-photon activated photodynamic therapy and imaging |
| abstract |
The present invention provides organically modified silica (ORMOSIL) nanoparticles into which have been incorporated two-photon absorption dye molecules. The two photon absorption dye displays a unique aggregation induced fluorescence enhancement behavior. As a result ORMOSIL nanoparticles with high amounts of the dye can be prepared. These particles can be used for imaging. In one embodiment, the nanoparticles can additionally have incorporated therein a photosensitizer. The photosensitizer can be activated by intraparticle fluorescence resonance energy transfer (FRET) from the dye aggregates resulting in enhanced fluorescence and singlet oxygen generation from photosensitizer under two-photon excitation conditions. Such nanoparticles can be used for photodynamic therapy applications. |
| priorityDate |
2006-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |