Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d01682c4f56a21a3dbbc05a71d371abb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d8d30805708f0d2affd52c695145421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fad04a3dfdcac1f331feeae6b8d0ad11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0e7dfce989565c19cd11d578c4cdf75 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
filingDate |
2007-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f116bc2aa3147ade293596b65099ad57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4221e93b13fb133cdaa4c4bdda08079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171113d83809854463bf7ea514307da0 |
publicationDate |
2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008028978-A1 |
titleOfInvention |
Nuclear receptor assay |
abstract |
The present invention relates to methods for measuring compound efficacy and potency on nuclear receptor-co-regulator interaction, comprising the steps of (a) co-incubating at least one nuclear receptor and at least one compound under conditions that allow interaction; (b) co-incubating the nuclear receptor-compound mixture of step (a) with an array of co-regulators, under conditions that allow compound modulated receptor-co-regulator interaction; (c) determination of compound- modulated receptor-co-regulator interaction in function of co-regulator concentration, and (d) determination of compound-modulated receptor-co-regulator interaction in function of compound concentration; wherein steps (c) and (d) are performed in a single assay. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013037972-A1 |
priorityDate |
2006-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |