| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_265682d08f28a5c916df289fa8d3da6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8169dac498b943292339a558c67917eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7754aee1582cadaa2c7813127677257a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e72b789767a0a64f22dbbfb4d6a2f08d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5767 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2007-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b11fb1831001605f255b7aa19bca7dfd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63035629c90cdaaca2ce399e046a881f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3596b974646a0bbbb1c117da7ca881e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75d545da6cc880625245114e68aecd9d |
| publicationDate |
2008-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008027944-A2 |
| titleOfInvention |
Antigenic protein conjugates and process for preparing same |
| abstract |
An improved process for the preparation of antigenic protein conjugates is provided. The conjugates preferably are formed through reaction with one or more free sulfhydryl groups in the antigenic protein. The process of the present invention preferably employs a trialkylphosphine as the reducing agent and allows for reduction of disulfide bonds in the antigenic protein and conjugation with a conjugate moiety, preferably in a single reaction vessel (i.e. 'in situ') because the process optimally does not require the removal of the reducing agent before subsequent addition of the sulfhydryl reactive agent. Antigenic protein conjugates prepared by the in situ process and their use in diagnostic immunoassays are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11370838-B2 |
| priorityDate |
2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |