| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0aded831b4eb8188cecbfc4adacdd6e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76a4701c8636c6a7a16ca4612510c33d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e20610bd7bf10c7c40e4af8d4534d4e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c8ae747339d3a41a82b17a29266d475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dad3284e3e267150b35c37be4f2cb5ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e16301ebf5dbc8a7e028b34dbc4f7eae |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 |
| filingDate |
2007-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42d495dbb83c04a649b8cdb8282fc7b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dc9da3b8fd6f68f730c06eba54013eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c192e4a08ec7483835d55c25b1440a0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fa3e41ad34244fa18888f1c6389f29e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d194dab975b2276e16cba3492dd8a660 |
| publicationDate |
2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008023390-A2 |
| titleOfInvention |
Modified release pharmaceutical composition of bupropion hydrochloride |
| abstract |
A delayed extended release pharmaceutical composition includes a compressed core containing an effective amount of bupropion or its pharmaceutically acceptable salt, a water-attractant polymer. The core is preferably devoid of a stabilizer. The core is surrounded by an extended release layer, which is free of plasticizer and pore-forming agent. The extended release layer is surrounded by a delayed release layer. Alternating coats of extended release layer and delayed release layer may follow. A preferred extended release layer includes ethylcellulose and hydroxypropyl cellulose or hydroxypropyl methylcellulose and a preferred delayed release layer includes methacrylic acid copolymer and hydroxypropyl methylcellulose phthalate, lactose and a combination of triethyl citrate and polyethylene glycol and talc. A method of preparing the delayed extended release bupropion hydrochloride containing pharmaceutical composition is also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2229053-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110200947-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2229053-A4 |
| priorityDate |
2006-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |