| abstract |
A process for the preparation of for the preparation of 5-hydroxyisoxazolidines, 5- isoxazo lidinones, β-amino acids, β-amino aldehydes and derivatives thereof, by reacting hydroxyl amines or hydroxyl carbamates with an α,β-unsaturated aldehyde or ketone in the presence of an amino compound as catalysts. The catalyst is preferably selected from amino acids, peptides and derivatives thereof, chiral pyrrolidines, protected diarylprolinol derivatives and acyclic and cyclic amines. |