http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008018783-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13a04118b990ad9596fb5c7a36ea02d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7daa3a44196cf06802d547d216f7a2ad |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 |
filingDate | 2007-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3492226fb42bf68416e3eb7d77c33b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cbd5e55fb626aabca7bfe5bb5d92e34 |
publicationDate | 2008-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2008018783-A2 |
titleOfInvention | Porphyrin activation by different spectrum electromagnetical waves-new malignant tumour treatment possibilities |
abstract | It is proved that hematoporphyrine derivatives (HpD) may be activated not only by visible or ultraviolet light, but also by electromagnetic oscillations of shorter wave length. While irradiating HpD solutions of different concentration with 405 nm light, we can see a visible crimson fluorescence. If at first HpD solutions (1 ml, 0,00001-0,0008 mg/ml) are irradiated by gamma rays (2 Gy, source - 60Co),and then are irradiated by 405 nm blue light, the fluorescence disappears. If to cover the said HpD solutions with calcium soda- lime glass at the time of gamma rays action, the fluorescence remains. The rats that were vaccinated with glioma C6, after injection of HpD and affecting the tumours with small gamma ray dose, a statistically reliable cured tumour regression was observed. During the time of irradiation the covered with calcium soda lime glass tumour growth was not impeded and the effect of treatment would disappear. The results let come to the conclusion that HpD is activated by those ionizing radiation spectrum rays that correspond positrons annihilation gamma quantum line 0,511 MeV in 60Co energetical gamma spectrum. With quantum of this energy, to activate HpD, only 0,020,2 Gy gamma ray dose is needed. |
priorityDate | 2006-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.