| abstract |
A putty form biomaterial composition made of a collagen scaffold and ceramic granule having improved flowable yet cohesive characteristics through the addition of, either individually or in some combination, polyhydroxy compounds, a liquid polyhydroxy compound ester, a liquid solution of solid polyhydroxy compound, a liquid solution of solid polyhydroxy compound ester to allow for use in surgical bone repair is presented. Specific polyhydroxy compounds, including polyethylene glycol polymers (PEG), PPO/PEO block co-polymers (i.e., a poloxamer NF grade), and the polysaccharides alginate and chitosan may be utilized. |