http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008016664-A3

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publicationDate 2008-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008016664-A3
titleOfInvention Compositions and methods for treating cancer with dacarbazine nanoemulsions
abstract A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anti-cancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when applied as a free solution.
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