| abstract |
Disclosed is a method for screening for a compound, comprising the step of detecting the binding between a vitamin D receptor and CDP. Specifically disclosed are: a novel method for the in vitro screening of a compound having a potent bone forming activity and few adverse side-effects; a compound involved in the differentiation of an osteoblast, which can be selected by the screening method; a therapeutic agent for a disease associated with the transcription activity enhanced by a complex of a vitamin D receptor and CDP through the vitamin D receptor, which comprises the compound; and a kit for use in the screening method. |