| abstract |
It is intended to obtain a new finding related to a mechanism of inducing differentiation of Th1/Th2/Th17 through dendritic cells, and to provide a pharmaceutical effective in an immunity-related disease by utilizing the finding, a screening method for the pharmaceutical, and an effective agent for regulating a mechanism of inducing differentiation of Th1/Th2/Th17 through dendritic cells. The invention relates to a pharmaceutical for treating or preventing a disease caused by the imbalance of Th, characterized by containing a compound that modifies the activity of dopamine receptor as an active ingredient, a screening method for the pharmaceutical, and various agents characterized by containing a dopamine D1-like receptor antagonist or a dopamine D2-like receptor antagonist as an active ingredient. |