http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008014916-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1055a7e6616c553c6553eef446e272b4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2007-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_975213ff4aad3959034268149bdd8953 |
| publicationDate | 2008-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008014916-A1 |
| titleOfInvention | Screening method for the isolation of centrosomal cluster-inhibitors as anti-cancer agents |
| abstract | Described is a method of screening for therapeutic agents useful in the treatment of a disease characterized by centrosome aberrations, preferably a solid neoplasia or a haematological malignancy, comprising the steps of (a) contacting a cell from a cell which harbours extra copies of centrosomes and divides in a bipolar fashion (centrosomal clustering) with a test compound; and (b) detecting an effect of said test compound on spindle polarity, wherein (i) induction or (ii) increase of the frequency of multipolar mitoses indicate that the test compound is effective as a drug for specific chemotherapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9498540-B2 |
| priorityDate | 2006-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.