abstract |
After liquids (B, Fig. 1; 506, Fig. 15) flow over probes (C, Fig. 1; 20, Fig. 4; A, B, C, Fig. 14) to form photo-emissive analyte complexes on a surface within a closed cassette (A, Fig. 1; 50, Fig.4; 502, Fig. 15) liquid is removed by flow, assisted by gas flow, then a sustained drying gas stream (B, Fig. 1; E, Fig. 2; 200 Fig. 4; 506, Fig. 15) is forced into the cassette, to flow over the complexes for a drying interval. Air heating assists the drying. Light (B, Fig. 1; 506, Fig. 15) from the analyte complexes is then read through a window. The desiccating gas stream is introduced to a passage extending from a bubble removal system (128) to probes (133). For wide arrays of probes, a common passage for liquid and desiccating gas connects through a widening transition to a wide reaction chamber (133). A reader station (Figs. 2A and 11A) includes air and liquid pumping devices. |