Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dea97595058f316a875c28a64efb90da http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be8ee051fd1b81eb3aef6c87d3b54be http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_522d16a104f3faab2802942ca523e494 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_830ad2726550a24952adf40d2737bb7b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 |
filingDate |
2007-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1e5143ba43a75cdf319870277268cfb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_313cd2ae9b6be822c73e4864b831e0a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3540d72b740516f84117ec619dccc29e |
publicationDate |
2008-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008012538-A2 |
titleOfInvention |
Live vaccine strains of francisella |
abstract |
A strain of Francisella species wherein a gene which encodes for part of the glutamate metabolic pathway has been inactivated, and which is able to produce a protective immune response in an animal, for use as live prophylactic or therapeutic vaccine against infection by said Francisella species. Particularly effective strains include those where the capB gene is deleted. Other embodiments of the invention describe strains which comprise a further genetic mutation wherein a gene which encodes for another component of the cell is also inactivated. Pharmaceutical compositions comprising said strains, together with methods which utilise such strains are also described and claimed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010129457-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8198430-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8206700-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008075075-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8790910-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609108-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2458057-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010129457-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8481024-B2 |
priorityDate |
2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |