Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc83b24f7a4ea01cf1863ea05cb68acc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8c38b7fb5a561eebb8886c7adbf1132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51bee3516d65530618b7916402e3d266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db17ffe6569bd387eaf867e12be57600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e94026029d280255b5f58773d1d7fd79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08fbd040478aef9cb3447349348862e1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 |
filingDate |
2007-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0644c5cf606e1cd29f7667f5c249b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1edd9128cc06ba7080c9814adc3dc63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55daef08294ffb015361f19d111ae77d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cb7b6b3592de68368a2be84b10f0688 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23b038b1c1fd1bc70f0610113ffb9221 |
publicationDate |
2008-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008012066-A2 |
titleOfInvention |
Novel peptide having antimicrobial activity |
abstract |
This invention relates to a peptide of the formula B-Cys-X-Lys-Lys-Z-Gly-B1X1 wherein: B is a sequence of 1-10 amino acid residues or an amino terminal group; X is a sequence of 1-4 amino acid residues which may be the same or different, the or each amino acid residue having a pK>7; Z is a sequence of 2-4 amino acid residues with the proviso that the first amino acid residue in the sequence and which is linked to the preceding lysine residue has a pK>7; B1 is a sequence of two amino acids, which may be the same or different, selected from lysine and/or arginine; and X1 is a sequence of 1-15 amino acid residues or a carboxy-terminal group comprising at least one amino acid residue having a polar, uncharged side chain or a positively charged side chain at pH 7.0 (pK>7); or a pharmaceutically acceptable salt thereof. The formula peptide has anti-microbial activity, especially anti-bacterial and anti-fungal activity. |
priorityDate |
2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |