http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008011437-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edc84e4b75a26ca33c0dc36dd165d835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6492c115fa4d962d2057903a898f7852 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-575 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2007-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c82175ec69a01674744959aa79d8b1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_817fb833419e804d23abb9507c610f52 |
publicationDate | 2008-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2008011437-A1 |
titleOfInvention | Gamma secretase notch biomarkers |
abstract | The present invention relates to the biomarker TFF-3 that measures y-secretase mediated Notch processing. TFF-3 has utility in predicting and/or determining in vivo Notch-related toxicity associated with inhibition of Notch processing mediated by -secretase. The reagents and methods of the invention can be utilized before, after, or concurrently with, pre-clinical, clinical, and/or post-clinical testing. The reagents and methods of the invention can be used to identify and maintain preferred doses of test compounds and thereby prevent medical complications, such as gastrointestinal cellular damage. |
priorityDate | 2006-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.