Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22f1081c4c8d6141ccd34a756fbe5ce1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32a7d219cfb6a16f4b86cd2218ac173d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4713 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2007-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0382260ebe8528b4d53a0f24b2ba4cb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ed39e87f527d922e13cdba00cfbf155 |
publicationDate |
2008-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008009977-A2 |
titleOfInvention |
Methods and compositions for modulating socs3 |
abstract |
The expression of suppressor of cytokine signalling 3 (SOCS3) in mammalian cells is controlled via modulating the expression and/or activity of Foxp3 in the cell. Modulation of Foxp3 homodimer formation or activity allows for control of SOCS3 expression. SOCS3 is an inhibitor of several intracellular signal transduction pathways, including the LIF signalling pathway. Modulators of Foxp3 homodimer activity and/or expression that are able to control the expression of SOCS3 in a cell are useful as immunomodulators. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846308-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11712454-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11713459-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11547718-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013151490-A1 |
priorityDate |
2006-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |