abstract |
Disclosed herein is a nucleic acid molecule of a mutant argF gene, which is involved in arginine biosynthesis. The protein product of the mutant argF gene, in which a partial nucleotide or amino acid sequence is substituted, has increased ornithine carbamoyltransferase activity. Also, disclosed are a recombinant vector containing the nucleic acid molecule and a cell transformed with the recombinant vector. Further, disclosed is a method of producing high levels of L-arginine by culturing the transformant. The recombinant microorganism provides an increased yield of L-arginine. |