| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fa18e617b8cb55846f831feea60d4bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aca1824e65461b02cda08eb8cd4bc4bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3451cbe4db3bfc6d8e9a93443efd6882
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc52125695e0d006a585d9ade545c6ed |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate |
2007-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01b3f4892285d43aad29dc6fcbdd83a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1adebbc50a7f3e76f49f2d38fc237f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de54f9c4e7214adf2b3a1e17814c1908 |
| publicationDate |
2008-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008006070-A2 |
| titleOfInvention |
Compounds and combinations thereof for inhibiting beta-amyloid production and methods of use thereof |
| abstract |
Provided are compounds which can be used in combination for treating diseases associated with a condition associated with cerebral accumulation of Alzheimer’s amyloid, such as Alzheimer’s disease. Also provided are methods of treating or reducing the risk of developing β-amyloid production, β-amyloid deposition, β-amyloid neurotoxicity (including abnormal hyperphosphorylation of tau) and microgliosis associated with cerebral accumulation of Alzheimer’s amyloid by administering therapeutically effective amounts of compounds which in combination can decrease β-amyloid production and capacitative calcium entry in cells. Further provided are methods for diagnosing diseases associated with cerebral accumulation of Alzheimer’s amyloid in animals or humans by administering diagnostically effective amounts of the compounds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9387206-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865769-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103044316-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809302-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10682342-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8741886-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9597297-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9636316-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10045971-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010515-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-024465-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9144558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10342768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10342784-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322163-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011054759-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9241933-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9248111-B2 |
| priorityDate |
2006-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |