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publicationDate 2008-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2008002278-A1
titleOfInvention Shg quantification of matrix-related tissue dynamic and disease
abstract A microscope (200) for optical imaging of high optical scattering coefficient biological tissue, comprising an optical excitation source (201) for irradiating a scan area of the sample (205) and generating optical emissions, wherein the sample has a first face facing away from the source and a second face facing the source. A two dimensional element (207) for scanning the light over the sample; a focussing element (209) having a numerical aperture NAi to focus the light onto the sample; a first optical condenser (213) to collect light from the first face, the collected light comprising source transmitted light and first optical emission generated in the sample, the condenser having a NA2 larger than NAi; an optical filter(215) to block the transmitted source light; an aperture with a size corresponding to the irradiated area of the sample, the aperture at the conjugate image position of the sample generated by the condenser; and an optical detector (217) collecting light from the first face for detecting the first optical emission from the scan area.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014029407-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011508889-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013030305-A1
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