http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008000223-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf5583d17de5870ee91f9bf3cdbcdddf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40db9f3b05d8c7aee815c2776fa288a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c087ca72c54cfd83d8bdf575f5056700 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-4833 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J3-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01J3-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 |
| filingDate | 2007-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb0cd9f4f5a6b0cdb172555f0b088a94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5928dbb43720296c591f8729932b6c82 |
| publicationDate | 2008-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008000223-A1 |
| titleOfInvention | Spatially-resolved measurement method for the detection of melanin in fluorophor mixtures in a solid sample |
| abstract | Known measurement methods use excitation wavelengths of 800 nm at ultra-short pulse lengths of 100 fs, with repetition rates of 80 MHZ and power densities of 100 GW/cm<SUP>2</SUP>. In such methods, simultaneous two-photon and three-photon excitations in the dangerous UV-C region are sometimes obtained. With the resulting fluorescence spectrum, neither the melanin in general, nor individual melanin types, can be clearly identified from the fluorophor mixture, as would be necessary for determining malignant melanomas in skin tissue. In addition, there is an acute risk of bleaching out and of carcinogenic action on the sample. To improve the differentiation capability for the various melanin types and to avoid the risks mentioned, the method according to the invention uses wavelengths of up to 900nm at pulse lengths of up to 2ns and single pulses with power densities less than 1 GW/cm<SUP>2</SUP>. With the characteristic maxima of 475 nm for eumelanin and 575 nm for pheomelanin, the elimination of the flavin fluorescence and the effect of the significant reduction in the total fluorescence in malignant melanomas in skin tissue, the unequivocal identification of these canbe achieved with the technique. |
| priorityDate | 2006-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.