| abstract |
A compound represented by the formula (I) or a salt thereof, which is useful as an active ingredient of a pharmaceutical for the prevention and/or treatment of a disease induced by the activation of STAT6 and/or NF-κB. (I) wherein R1, R2, R3 and R4 independently represent a hydrogen atom, a halogen atom, a cyano group, a nitro group, a C1-4 alkyl group, a halogenated C1-4 alkyl group, or a C1-4 alkoxy group; R5 represents a halogen atom, a cyano group, a C1-4 alkyl group, a halogenated C1-4 alkyl group, or a C1-4 alkoxy group; R6represents a C5-7 cycloalkyl group, a substituted C5-7 cycloalkyl group, a completely saturated 5- to 7-membered heterocyclic group or a substituted, completely saturated 5- to 7-membered heterocyclic group; X represents a single bond, an oxygen atom, a sulfur atom, NR7, -O-CH2 or –N(R8)-CH2-; R7 represents a hydrogen atom or a C1-4 alkyl group, or together with a substituent in R6 forms a single bond, a methylene group or an ethylene group; and R8 represents a hydrogen atom, a C1-4 alkyl group, or a C7-12 aralkyl group. |