abstract |
An FKI-3389 substance is produced by culturing a microorganism (NITE ABP-244), which is a filamentous bacterium and has an ability to produce the FKI-3389 substance, in a medium, accumulating the FKI-3389 substance in the culture and isolating the FKI-3389 substance from the culture. Since the thus obtained FKI-3389 substance of the invention inhibits an NADH-fumarate reductase activity, it can be used as a composition for treating or preventing helminthic infection, therefore, it is expected to be a substance effective as a pharmaceutical product, an animal drug or an agricultural chemical. |