| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_034a60f3515ce462726eb14b3ea7015d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbed29e8c059c33e8c211c77a4b2f541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24fbb34ba1b3d0e8c5208af079aa3f33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cae93d8d9a68edc82082a5e9df06eb83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f077788667aab5c38c442fb6aeb1f0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91045 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2007-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a1b2d8f5a66f088affd2578c9c0b196
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7992a899a5982381b802fa24d7fdb289
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8647ee0c4c4b0c9249affcd3a9bc2d96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b6a7cdf3a87c732ca5c97c60f155636 |
| publicationDate |
2007-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007148106-A2 |
| titleOfInvention |
Detection of acetylation of prokaryotic proteins by mass spectrometry |
| abstract |
A method of identifying an N-terminally acetylated protein in a bacterium, the method comprising providing details of at least one putative translation start site (TSS) for at least one protein expressed in the bacterium, confirming the actual TSS of the at least one protein using mass spectrometry (MS), and determining whether the at least one protein is N-terminally acetylated using MS. A method of identifying an N-terminally acetylated protein in a bacterium, the method comprising providing a mutant strain of the bacterium comprising at least one protein N-acetyl transferase (pNAT) in mutant form, providing a wild-type strain of the bacterium comprising the at least one pNAT in wild-type form, and identifying a protein that is differentially N-terminal acetylated between the mutant and wild-type bacterial strains. A method of identifying a drug discovery target in a pathogenic bacterium, the method comprising determining at least one property of an N-terminally acetylated protein expressed in a pathogenic bacterium and which is relevant to the pathogenicity of the pathogenic bacterium. A method of identifying a bacterial pNAT. A method of screening for an inhibitor of a bacterial pNAT. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8999896-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011088421-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011088421-A3 |
| priorityDate |
2006-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |